Immunopathology in ocular toxoplasmosis: facts and clues

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Immunopathology in ocular toxoplasmosis: facts and clues.

Although parasite-mediated host cell lysis is deemed to be an important cause of tissue destruction in ocular toxoplasmosis (OT), the severity of the disease is probably correlated with hypersensitivity and inflammation. Notwithstanding, the mechanisms that regulate the inflammatory process in recurrent OT are poorly understood. Recent evidence has identified interleukin (IL) 17 as a marker for...

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Ocular toxoplasmosis

A large amount of research has been done on toxoplasmosis in the last 30 years, and the world-wide incidence of the infection, and its clinical manifestations, are recognized and documented in an extensive literature. New discoveries concerning the life-cycle of the organism (Frenkel, I970; Hutchison, Dunachie, Siim, and Work, I970) promise to solve many of the problems of the transmission of i...

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Ocular Toxoplasmosis

Address for Correspondence: Dr. Jyothirmay Biswas, Head of the Department of Ocular-Pathology and Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, 18, College Road, Chennai-600 006, E-mail: [email protected] Toxoplasmosis is the most common cause of posterior uveitis in many parts of the world. Prevalence is more in tropical countries than cold areas. 1,2 It is caused by Toxopla...

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Ocular toxoplasmosis.

Dear Editor: Acquired Toxoplasma gondii ocular infection usually presents with necrotizing retinochoroiditis with dense vitritis and vasculitis. Atypical disease has been observed in im-munocompromised states such as malignancy and AIDS 1 or after iatrogenic systemic 2 or local 3 immunosuppression. Intravitreal triamcinolone acetonide (TA) is used frequently by ophthalmologists for conditions l...

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Ocular toxoplasmosis

A large amount of research has been done on toxoplasmosis in the last 30 years, and the world-wide incidence of the infection, and its clinical manifestations, are recognized and documented in an extensive literature. New discoveries concerning the life-cycle of the organism (Frenkel, I970; Hutchison, Dunachie, Siim, and Work, I970) promise to solve many of the problems of the transmission of i...

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ژورنال

عنوان ژورنال: Memórias do Instituto Oswaldo Cruz

سال: 2009

ISSN: 0074-0276

DOI: 10.1590/s0074-02762009000200014